i run wine notepad success, under ntfs,but other can't work,as ie

gprotection

my file syetem type is ntfs,i install codeweavers-wine-2002++++,
now i am writing under "wine notepad",but i can't run iexplore,qq!
i see someone say wine can't work under ntfs,but my notepad do!
but why other application can't work?
so disapointed.
winxp en edition ,rh8 2.4.20